| vs. #22 Series History | ||
| Games: 5 | ||
| Overall Record: 5-0 (100%) Conference Record: 4-0 (100%) | ||
| Home: 2-0 (100%) Away: 2-0 (100%) Neutral: 1-0 (100%) | ||
| Lane Stadium: 2-0 (100%) Under Philip Montgomery: 0-0 (0%) | ||
| Televised Games: 5-0 (100%) | ||
| VT Ranked: 3-0 (100%) Opponent Ranked: 5-0 (100%) Both Teams Ranked: 3-0 (100%) | ||
| VT Ranked Higher: 3-0 (100%) Opponent Ranked Higher: 2-0 (100%) | ||
| Date | Opponent | Site | Score (VT-Opp) | Rank | TV | 
|---|---|---|---|---|---|
| Sat., Nov 9, 2019 | Wake Forest | Blacksburg, Va. * | W, 36-17 | NR/22 | ACC Network | 
| Sat., Sep 29, 2018 | Duke | Durham, N.C. * | W, 31-14 | NR/22 | ESPN2 | 
| Sun., Sep 3, 2017 | West Virginia | Landover, Md. | W, 31-24 | 21/22 | ABC | 
| Sat., Oct 6, 2007 | Clemson | Clemson, S.C. * | W, 41-23 | 15/22 | ESPN | 
| Fri., Nov 26, 1999 | Boston College | Blacksburg, Va. * | W, 38-14 | 2/22 | CBS (national) | 
| Total | 177-92 | ||||
| Average | 35-18 | ||||
| Most Points Scored | 41/24 (2007/2017) | ||||
| Fewest Points Scored | 31/14 (2018/2018) | ||||
| Shutouts By | - / - ( - / - ) | ||||
| Largest Margin of Victory | 24/ - (1999/ - ) | ||||
| Smallest Margin of Victory | 7/ - (2017/ - ) | ||||