| vs. #Top5 Series History |
| Games: 34 |
| Overall Record: 1-33 (2.9%) Conference Record: 1-10 (9.1%) |
| Home: 1-7 (12.5%) Away: 0-17 (0%) Neutral: 0-9 (0%) |
| Lane Stadium: 1-7 (12.5%) Under Brent Pry: 0-1 (0%) |
| Televised Games: 1-24 (4%) |
| VT Ranked: 1-13 (7.1%) Opponent Ranked: 1-33 (2.9%) Both Teams Ranked: 1-13 (7.1%) |
| VT Ranked Higher: 0-2 (0%) Opponent Ranked Higher: 1-31 (3.1%) |
| Date | Opponent | Site | Score (VT-Opp) | Rank | TV |
|---|
| Sat., Oct 7, 2023 | Florida State | Tallahassee, Fla. * | L, 17-39 | NR/5 | ABC |
| Sat., Dec 5, 2020 | Clemson | Blacksburg, Va. * | L, 10-45 | NR/4 | ABC |
| Sat., Sep 30, 2017 | Clemson | Blacksburg, Va. * 1 | L, 17-31 | 12/2 | ABC |
| Sat., Dec 3, 2016 | Clemson | Camping World Stadium, Orlando, Fla. 2 | L, 35-42 | 19/3 | ABC |
| Mon., Sep 7, 2015 | Ohio State | Blacksburg, Va. 3 | L, 24-42 | NR/1 | ESPN |
| Sat., Aug 31, 2013 | Alabama | Atlanta, Ga. 4 | L, 10-35 | NR/1 | ESPN |
| Mon., Jan 3, 2011 | Stanford | Miami Gardens, Fla. 5 | L, 12-40 | 12/5 | ESPN |
| Mon., Sep 6, 2010 | Boise State | FedExField, Landover, Md. | L, 30-33 | 10/3 | ESPN/ESPN3D |
| Sat., Sep 5, 2009 | Alabama | Atlanta, Ga. 6 | L, 24-34 | 7/5 | ABC |
| Thu., Oct 25, 2007 | Boston College | Blacksburg, Va. * | L, 10-14 | 8/2 | ESPN (national) |
| Sat., Sep 8, 2007 | LSU | Baton Rouge, La. | L, 7-48 | 9/2 | ESPN |
| Sat., Nov 5, 2005 | Miami | Blacksburg, Va. * 7 | L, 7-27 | 3/5 | ESPN (national) |
| Mon., Jan 3, 2005 | Auburn | New Orleans, La. 8 | L, 13-16 | 9/3 | ABC (national) |
| Sat., Aug 28, 2004 | Southern California | FedExField, Landover, Md. 9 | L, 13-24 | NR/1 | ESPN (national) |
| Sat., Nov 1, 2003 | Miami | Blacksburg, Va. * | W, 31-7 | 10/2 | ESPN (national) |
| Sat., Dec 7, 2002 | Miami | Miami, Fla. * | L, 45-56 | 18/1 | ABC (national) |
| Sat., Dec 1, 2001 | Miami | Blacksburg, Va. * | L, 24-26 | 14/1 | ABC (national) |
| Sat., Nov 4, 2000 | Miami | Miami, Fla. * | L, 21-41 | 2/3 | CBS (national) |
| Tue., Jan 4, 2000 | Florida State | New Orleans, La. 10 | L, 29-46 | 2/1 | ABC (national) |
| Sat., Sep 18, 1993 | Miami | Miami, Fla. * | L, 2-21 | NR/3 | Sunshine Network (Florida) |
| Sat., Oct 24, 1992 | Miami | Blacksburg, Va. * | L, 23-43 | NR/1 | BIG EAST Network (regional) |
| Sat., Oct 12, 1991 | Florida State | Orlando, Fla. | L, 20-33 | NR/1 | BIG EAST Network (regional) |
| Sat., Sep 29, 1990 | Florida State | Tallahassee, Fla. | L, 28-39 | NR/2 | |
| Sat., Nov 12, 1988 | Florida State | Tallahassee, Fla. | L, 14-41 | NR/5 | |
| Sat., Sep 3, 1988 | Clemson | Clemson, S.C. | L, 7-40 | NR/4 | Jefferson-Pilot (regional) |
| Sat., Nov 14, 1987 | Miami | Miami, Fla. | L, 13-27 | NR/3 | |
| Sat., Oct 26, 1985 | Florida | Gainesville, Fla. | L, 18-35 | NR/2 | |
| Sat., Oct 15, 1983 | West Virginia | Morgantown, W.Va. | L, 0-13 | NR/4 | CBS (regional) |
| Sat., Nov 8, 1980 | Florida State | Tallahassee, Fla. | L, 7-31 | NR/3 | ABC (regional) |
| Sat., Oct 27, 1979 | Alabama | Tuscaloosa, Ala. | L, 7-31 | NR/1 | |
| Sat., Oct 28, 1978 | Alabama | Tuscaloosa, Ala. | L, 0-35 | NR/3 | |
| Sat., Oct 27, 1973 | Alabama | Tuscaloosa, Ala. | L, 6-77 | NR/2 | |
| Sat., Nov 18, 1972 | Alabama | Tuscaloosa, Ala. | L, 13-52 | NR/2 | |
| Sat., Oct 30, 1948 | Army | West Point, N.Y. | L, 7-49 | NR/5 | |
| Total | 544-1213 |
| Average | 16-36 |
| Most Points Scored | 45/77 (2002/1973) |
| Fewest Points Scored | 0/7 (1983/2003) |
| Shutouts By | - /2 ( - /1983) |
| Largest Margin of Victory | 24/71 (2003/1973) |
| Smallest Margin of Victory | 24/2 (2003/2001) |
Notes:
* - Conference game
1 - Maroon Effect in Blacksburg, Va.
2 - ACC Championship in Camping World Stadium, Orlando, Fla.
3 - Orange Effect in Blacksburg, Va.
4 - Chick-fil-A Kickoff Game in Atlanta, Ga.
5 - Orange Bowl in Miami Gardens, Fla.
6 - Chick-fil-A Kickoff Game in Atlanta, Ga.
7 - Maroon Effect in Blacksburg, Va.
8 - Sugar Bowl in New Orleans, La.
9 - BCA Football Classic in FedExField, Landover, Md.
10 - Sugar Bowl in New Orleans, La.