| vs. #16 Series History |
| Games: 10 |
| Overall Record: 5-5 (50%) Conference Record: 3-1 (75%) |
| Home: 3-2 (60%) Away: 1-1 (50%) Neutral: 1-2 (33.3%) |
| Lane Stadium: 3-2 (60%) Under Brent Pry: 0-0 (0%) |
| Televised Games: 5-3 (62.5%) |
| VT Ranked: 5-2 (71.4%) Opponent Ranked: 5-5 (50%) Both Teams Ranked: 5-2 (71.4%) |
| VT Ranked Higher: 5-1 (83.3%) Opponent Ranked Higher: 0-4 (0%) |
| Date | Opponent | Site | Score (VT-Opp) | Rank | TV |
|---|
| Sat., Nov 2, 2019 | Notre Dame | Notre Dame, Ind. | L, 20-21 | NR/16 | NBC |
| Sat., Nov 24, 2007 | Virginia | Charlottesville, Va. * | W, 33-21 | 8/16 | ESPN2 |
| Sat., Nov 27, 2004 | Virginia | Blacksburg, Va. * | W, 24-10 | 11/16 | ABC (regional) |
| Thu., Sep 12, 2002 | Marshall | Blacksburg, Va. | W, 47-21 | 11/16 | ESPN (national) |
| Mon., Jan 1, 2001 | Clemson | Jacksonville, Fla. 1 | W, 41-20 | 6/16 | NBC (national) |
| Sat., Oct 16, 1999 | Syracuse | Blacksburg, Va. * 2 | W, 62-0 | 4/16 | ESPN (national) |
| Sat., Nov 28, 1998 | Virginia | Blacksburg, Va. | L, 32-36 | 20/16 | ESPN (national) |
| Sat., Nov 19, 1994 | Virginia | Blacksburg, Va. | L, 23-42 | 14/16 | BIG EAST Network (regional) |
| Sat., Oct 4, 1952 | Virginia | Roanoke, Va. | L, 0-42 | NR/16 | |
| Sat., Oct 23, 1948 | Duke | Roanoke, Va. * | L, 0-7 | NR/16 | |
| Total | 282-220 |
| Average | 28-22 |
| Most Points Scored | 62/42 (1999/1994) |
| Fewest Points Scored | 0/0 (1952/1999) |
| Shutouts By | 1/2 (1999/1952) |
| Largest Margin of Victory | 62/42 (1999/1952) |
| Smallest Margin of Victory | 12/1 (2007/2019) |
Notes:
* - Conference game
1 - Gator Bowl in Jacksonville, Fla.
2 - Homecoming in Blacksburg, Va.